Organ Transport Solutions

Paragonix Technologies' primary goal is to improve transplant patient outcomes and optimize donor organ utilization.

Organ Transport Solutions

Paragonix Technologies primary goal is to improve transplant patient outcomes and optimize donor organ utilization.

Organ Transport Solutions

Current Methods for Transporting Donor Organs are Outdated and Unpredictable

Current Methods for Transporting Donor Organs are Outdated and Unpredictable

Problem

Current Cooler Method Provides Unpredictable Donor Organ Cooling

Rapid Temperature Decrease to Below 2°C

  • Multi-center clinical study found average organ temperature during ice cooler transportation (n=186) was below 2°C and below 0°C after 6 hours1
  • Preclinical porcine study found apex temperature below 2°C in 30 minutes and ventricle below 2°C in 150 minutes2
  • Preclinical cardiac canine study found right ventricle, left ventricle, and septum below 1°C in 75 minutes and below 0°C in 4 hours3

Known Risks Below 2°C

< 2°C: Cold injury 4-7

Known Cardiac Risks Below 2°C

< 1°C: Irreversible suppression of diastolic function8

< 0°C: Proteins denature 4-7

Donor Organ Transport on Ice

Paragonix Provides an Advanced Solution

ICE STORAGE

  • Historic method of preserving and transporting organs
  • Uses plastic bags, ice, and consumer ice coolers
  • Non-FDA regulated devices
  • Un-controlled, un-monitored cooling
  • Risks cellular injury to transported organ
Paragonix Logo
  • FDA cleared and CE marked device for preservation and transportation of donor organs
  • Repeatable process to protect donor organ in transit
  • Real-time monitoring, tracking, and communication
  • Over 900 organs preserved since 2019
Paragonix Organ Transport Solutions

How it Works

Paragonix SherpaPak®

CARDIAC TRANSPORT SYSTEM

Paragonix SherpaPak Cardiac Transport System Breakdown

Paragonix LUNGguard™

DONOR LUNG PRESERVATION SYSTEM

Paragonic LUNGguard Breakdown

Paragonix SherpaPak® CTS

Cardiac Transport System Features

Precision Cooling System

Paragonix SherpaCool™ ribbons’ proprietary phase change technology prevent exposure to excessive temperature reduction

SherpaPak Icon

Mechanically Isolated Protection

Rigid, pressure controlled, leakproof dual-canister system protects heart from physical and thermal trauma

Stable Preservation Environment

Lightweight shipper system is validated for a consistent thermal environment for over 40 hours

Connected Data Driven Monitoring

Real-time monitoring and data reporting via Bluetooth® connection and the Paragonix App

Caution: Federal (US) law restricts this device to sale by or in the order of a licensed health care practitioner. Please refer to Instructions for Use for full prescribing information. Cleared indication is for 4-hour use. Patents issued and pending. See Indications For Use for more information.

SherpaPak Cardiac Transport System with App

Paragonix LUNGguard™ CTS

Donor Lung Preservation System Features

LUNGguard Donor Lung Preservation System with App

Stable Temperature Between 4-8°C

The LUNGguard system is validated to maintain temperatures of donor lungs between 4-8°C for over 44 hours.

A Safety Vault for Donor Lungs

Lungs are placed inside a secure vault to maintain the shape of the lungs and prevent physical trauma during transport

Organ Temperature Monitoring

The lungs are placed on a tray with an embedded temperature probe that continuously measures the temperature of the preservation solution

Connected Data Driven Monitoring

Real-time monitoring and data reporting via Bluetooth® connection and the Paragonix App

Caution: Federal (US) law restricts this device to sale by or in the order of a licensed health care practitioner. Please refer to Instructions for Use for full prescribing information. Cleared indication is for 8-hour use. Patents issued and pending. See Indications For Use for more information.

Advancing Donor Organ Preservation

Heart Organ Transplant

HEART

Paragonix SherpaPak Cardiac Transport System

SherpaPak

Cardiac Transport System

Learn More
Lung organ transplant

LUNG

Paragonic LUNGguard

LUNGguard

Donor Lung Preservation System

Learn More
liver organ preservation

LIVER

Paragonix LIVERguard Liver Transport System

LIVERguard

Donor Liver Preservation System

Coming Soon
Kidney organ transplant

KIDNEY

Paragonix SherpaPak Kidney Transport System

Kidney KTS

Kidney Transport System

Coming Soon

PANCREAS

Paragonix SherpaPak Pancreas Transport System

Pancreas PTS

Pancreas Transport System

Coming Soon
1. Horch et al., Transplant Proceed 2002
2. Validation data on file with Paragonix Technologies
3. Hendry et al., J Thorac and Cardiovasc Surg 1989
4. Michel et al. Ann Transplant 2014
5. Michel et al. Ann Transplant 2015
6. Ingemansson et al., Ann Thorac Surg 1996
7. Mankad et al., J Thorac and Cardiovasc Surg 1992
8. Keon et al., Ann Thorac Surg 1988

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